Take a look at our growing podcast and webinar audio series.
New tools and approaches are allowing us an unprecedented view of how the neural circuits develop and function in vivo. Combining new high resolution microscopy techniques and optical probes and indicators with transgenic and viral methods for manipulating gene expression in specific cell types in vivo, we can now track neural circuit dynamics in vivo in real time. In this podcast, Jeff Lichtman (Harvard) and Karel Svoboda (Janelia Farm, HHMI) discuss with Emilie Marcus and Katja Brose how these new in vivo imaging methods are revolutionizing the way we think about the brain.
Neural circuits are a fundamental unit of computation in the nervous system and thus an important focus of neuroscience research. Recent years have seen tremendous advances in the mapping of circuit architecture as well as the monitoring and manipulation of its function. New insights into the logic of neural circuits and how they mediate behavior will be the focus of the forthcoming Cell symposium on "Genes, Circuits, and Behaviour" in June (www.cell-symposia-genes-circuits-behavior.com). This webinar will showcase approaches from various systems aimed at understanding how neural circuits function “in action” during perception, action, and cognition. We hope that you will join us for the chance to hear from Scott Sternson and Ed Callaway.
Performance calculations in the design of an optical coating assume ideal conditions. Light is precisely collimated and monochromatic, and layers have exact thicknesses and optical constants. A manufactured coating departs from perfection. Performance measurement uses illumination with finite aperture and bandwidth. In use, the coating is subject to illumination and environment still less well controlled. The resulting effects can sometimes be surprising but they are not mysterious and can be readily predicted.
We are pleased to provide a presentation by and discussion with Steven Block from Stanford University. In the podcast, you will learn about a variety of ways that optical tweezers have been applied to understanding the complex behavior of kinesins, RNA polymerases, and riboswitches at the single-molecule level. Also stay tuned through the end of the presentation to hear the follow up interview between Laura Finzi of Emory University and Steven as they discuss his career and his views on where the field and technology is heading next.
In this episode, researchers Ed Boyden from MIT and Jean Bennett from the University of Pennsylvania discuss the development of optogenetics and recent clinical applications, especially for the treatment of retinal disease. Also, in our science roundtable with science writers Sarah C.P. Williams and Ashley Yeager, we discuss neurobiology, the 2012 Nobel Prize winners, and DNA sequencing in outer space.
Fluorescent proteins have become invaluable tools for fluorescent microscopy in the life sciences but researchers still have many practical questions about using them. Three experts in the development and use of fluorescent proteins and sensors discuss these challenges and provide practical advice to users.