This series of multi-band filter sets feature our high performance ET sputter coatings. Included are dual, triple and quad-band sets, all of which use single-band excitation and emission filters. These require the use of filter wheels or sliders, or image-splitting devices to hold multiple individual filters. The polychroic beamsplitters remain stationary in a filter cube or similar holder. These sets are image-registered and are particularly useful for co-localization studies, FRET, and simultaneous imaging in live cell applications using image-splitting devices.