Human Breast Epithelial Cells

Human Breast Epithelial Cells In 3-Dimensional Culture Form Organized And Polar Structures
As in this image, non-malignant breast epithelial cells form polar structures that resemble the ‘acini’ that exist in vivo. This occurs in 3-dimensional extracellular matrix gels
that contain a high concentration of the basement membrane molecule laminin iii. However, cancerous breast cells form tumor-like structures in the same gels, making this an
easy assay to distinguish normal and malignant cells.

The assay was developed in the laboratories of Petersen and Bissell (PNAS, 1992).

Filters by:
Chroma Technology Corp