SKY (Spectral Karyotyping of Human Chromosomes)
Spectral karyotyping of human chromosomes. The image shows a normal metaphase plate after the simultaneous hybridization of 24 differentially labeled chromosome painting probes. The image was acquired using spectral imaging (a combination of Fourier spectroscopy and CCD-imaging) through a custom-designed filter cube from Chroma Technology Corp. A classification algorithm then allows the assignment of spectra-specific color to all chromosomes. SKY® is a registered trademark of Applied Spectral Imaging.